Edge peptide therapy is a new and promising treatment that targets cellular senescence to promote health and longevity. Cellular senescence refers to when cells stop dividing and enter a state of suspended animation. This build-up of senescent cells contributes to aging and age-related disease.
Edge peptides are short chains of amino acids that selectively induce death of senescent cells while leaving healthy cells unaffected. They help clear the body of these zombie-like senescent cells. Research shows that edge peptides may enhance healthspan and lifespan in animals. Human trials are now underway to translate these findings.
Some key points about edge peptide therapy:
- Targets senescent cells: Selectively eliminates senescent cells and avoids harming healthy cells. Reducing senescent cell burden is a promising anti-aging strategy.
- Enhances cardiometabolic health: Improves cardiovascular and metabolic parameters in mouse models of natural aging and diabetes.
- Extends healthspan: Increases resilience, fitness and physical function in aged mice.
- Well-tolerated: Has not shown any observable adverse effects in animal studies so far.
How does it work?
The exact mechanisms are still being unraveled but edge peptides appear to:
- Bind to senescent cells via cell surface markers that are uniquely expressed on them
- Initiate senescent cell apoptosis and clearance by the immune system
Current status and future directions
- First-in-human trial ongoing: Early results show good safety profile so far
- Therapeutic effects and optimal dosing being evaluated
- Combination therapies being explored - edge peptides plus:
- Senolytics (drugs that target senescent cells)
- NAD boosters
- mTOR inhibitors
- Possibility for transformative impact on healthspan and longevity
Revive Hormone Clinic
At Revive Hormone Clinic(), we offer cutting-edge peptide therapies to help you live healthier for longer. If you are interested in edge peptide therapy and want to find out if you may be a suitable candidate, sign up for a consultation with one of our physician specialists.
Our clinic focuses on:
- Personalized care
- Latest scientific advances
- Anti-aging and longevity
- Enhancing healthspan
- Improving quality of life
Contact us today to learn more!